Wave reflection: More than a round trip

Title: Wave reflection: More than a round trip
Creator: Afkhami, Rashid; Johnson, Sarah
Relation: Medical Engineering and Physics Vol. 92, Issue June 2021, p. 40-44
Publisher Link: http://dx.doi.org/10.1016/j.medengphy.2021.04.005
Publisher: Elsiver
Resource Type: journal article
Date: 2021
Description: Reflected pressure waves are key to the understanding of vascular ageing, a prominent factor in major cardiovascular events. Several different metrics have been proposed to index the effect of wave reflection on the pressure waveform and thereby serve as an indicator of vascular ageing. The extent to which these indices are influenced by factors other than vascular health remains a matter of concern. In this paper, we use transmission-line theory to derive a mathematical model for the reflection time (T_refl), and the augmentation index (AI), assuming a general extended model of the arterial system. Then, we test the proposed model against values reported in the literature. Finally, we discuss insights from the model to common observations in the literature such as age-related “shift” in the reflection site, the variation of AI with heart rate, and the flattening of T_refl in older participants.
Subject: ageing; arteries; reflection time; wave reflection; augmentation index; blood pressure
Identifier: http://hdl.handle.net/1959.13/1449470
Identifier: uon:43670
Identifier: ISSN:1350-4533
Language: eng
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